VThunter

Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

Jaagsiekte sheep retrovirus

Family: Reoviridae

Receptor: HYAL2

Receptor HYAL2 information

Summary: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0035	2021.04	10X Genomics	Duodenum	Normal	1482	Link
Vthunter_0036	2021.04	10X Genomics	Esophagus	Normal	24581	Link
Vthunter_0037	2021.04	10X Genomics	Heart	Normal	12958	Link
Vthunter_0038	2021.04	10X Genomics	Kidney	Normal	4481	Link
Vthunter_0039	2021.04	10X Genomics	LargeIntestine	Normal	3328	Link
Vthunter_0040	2021.04	10X Genomics	Liver	Normal	5694	Link
Vthunter_0041	2021.04	10X Genomics	Lung	Normal	13720	Link
Vthunter_0042	2021.04	10X Genomics	Spleen	Normal	3207	Link
Vthunter_0043	2021.04	10X Genomics	Stomach	Normal	12485	Link